What are the reasons for misjudgement of the tragedy in Japan Oman in the 2019 Asian Cup (Figure)

WhatarethereasonsformisjudgementofthetragedyinJapanOmaninthe2019AsianCup(Figure)At21:30onJanuary13,2019,Beijingtime,theAsianCupGroupFusheredinthefo

What are the reasons for misjudgement of the tragedy in Japan Oman in the 2019 Asian Cup (Figure)
At 21:30 on January 13, 2019, Beijing time, the Asian Cup Group F ushered in the focus battle, winning the hot topic Japan faced the West Asian powerhouse Oman team.At the end of the halftime match, the Japanese team relied on Haraguchi to shoot the deadlock and temporarily lead Oman 1-0.(China Messi Wu Lei scored twice) (Wu Lei profile) (All rounds of the first round of competition) (Asian Cup match schedule) (2019 Asian Cup match result prediction) (Asian Cup previous championship country) (National Football Team latest 25National People’s Congress) (National Football Team prepares for the Asian Cup to stay at a super five-star hotel) (Asian Cup referee list) (Asian Cup coaches from various countries in the Asian Cup) (National Football 2-1 Kyrgyzstan) (Group C latest standings) The 2019 Asian Cup group stage is coming to an end  Throughout the first half of the game, the Japanese team had more opportunities. The original energy once hit the door frame, and Nanye Tuoshi also wasted a lot of good opportunities.However, the Oman team is not without the opportunity to break.At the end of the first half of the game, Oman made a volley in the penalty area and Chang Youyou blocked the ball with his hand when they fell to the ground!However, the referee will not award a penalty, which also caused strong dissatisfaction with Omani players.The Asian Cup massacre handball was wrongly judged for the current Asian Cup. There is no VAR traceability system in the group stage, and it will not be activated until 1/8.Therefore, during the stage of the group stage, the referee had too many controversial penalties.It’s just that the Japanese team’s handball is too obvious this time, I wonder why the referee can miss it?  Seeing this scene, many Chinese fans remembered the 2004 local Asian Cup.In that Asian Cup, the Chinese team crossed five stages and cut six, and finally met with the Japanese team finals.In the final, the two sides once reached a 1-1 draw.The balance was broken by a controversial scene in the 66th minute.Toshio Nakamura’s free kick made a killing shot, and Hiroshi Nakada staged the hand of God to score the goal, but the referee ruled that the score was valid. This kind of wrong submission method lost the championship at home and since then Chinese football has also covered upEndless trough! Original title: Dispute penalty + escape point!Misjudgment in the Asian Cup, the Japanese team is a profiter

[Is there any genetically modified sesame seeds?]

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[Baseball monthly baby drinking water]_ children _ normal amount

[Baseball monthly baby drinking water]_ children _ normal amount

Be sure to add more water at this age, but do n’t overdo it, because many parents do not control well, and often cause children to drink too much or too little water, which is bad for the body. Most babies drink waterThe amount should be controlled within a normal range, not only to drink water, but also to promote the health of all aspects of the child’s body, not the amount of water to drink, including the amount of water introduced from fruit juices and food, which are all included in the calculation.

The amount of water the baby drinks is considered normal. The metabolism of children is particularly strong, and they need more water than adults. The younger the baby, the more water he needs.

The main sources of water are plain water, fruit juice, meal juice, and food (including milk).

In terms of weight per kilogram, the amount of fluid a baby needs is roughly 120?
150 ml, is 100 for toddlers?
140 ml.

The baby’s daily water consumption can be calculated. Multiply the weight (ton) by 120?
150 ml, get the total amount of liquid per day, and then re-drink the baby’s milk and water in the food, you can get the baby’s daily water consumption.

Normally, your baby’s intake and discharge are balanced.

Even if it can be slightly more, it will be excreted from the urine.

Since the water that is usually fed to your baby does not contain salt, it will not increase the burden on the kidneys, and you do not have to waste too much.

Babies do not like to drink water for the following reasons: 1. When supplementing calcium for babies in infants, some calcium supplement products can be taken by infants and young children, so many other ingredients are added to increase the taste of calcium supplement products.

Moms think that infants and young children love to eat, but they do not know that calcium for infants and young children should not be too sweet, which will cause taste substitution, affect the baby’s normal drinking water and milk, and even affect appetite.

2. Many children do not like to drink water. The cause of this problem should be transferred to the infant acceptance period. Due to the lack of scientific knowledge, many parents did not pay attention to supplement the child with sufficient water during the infancy period. As a result, the child did not like water.Habit; 3, the baby’s ability to take care of himself is preliminary perfect, and some parents worry that the child will drink more water and cause an increase in urination, intentionally or unintentionally reducing the baby’s drinking water;

You should also drink water for an approximate period of time. You should avoid not drinking one day and drinking a lot at a time.

We all understand the reason to eat on time every day, and to take medicine on time when you are sick, but how many people have paid attention to drinking water on time?

After we understand the relationship between water and nutrition, water and health, we should notice that the baby should drink water on time.

Observe the foot and observe the health

Observe the foot and observe the health

Introduction: The human body is an organic whole. Traditional Chinese medicine believes that the human body has a complex meridian system that connects and communicates with the entire body. Whether a disease occurs in an organ or system, it will affect the health of the whole body. The feet are no exception.Diseases not only affect the health of the whole body, but also can be reflected in the feet, showing abnormal phenomena.

Normal toenails are smooth, translucent, shiny, and slightly curved, a symbol of health.

The toenails become uneven, thin, and have longitudinal grooves, or even peeling, indicating that the human body is malnourished; nail nails are embedded in the meat or are hook-shaped, often indicating polyneuritis, neurasthenia, or vasculitis; etc.Usually, you should check the liver and kidney for chronic diseases; nails become bruises, often with circulatory system disorders; pale toenails are anemia; toenails numbness is a manifestation of cardiovascular disease.

The toes are plump, plump and elastic, which is a manifestation of health.

If the toenail of the jaw is often swollen, it should be carefully examined to rule out diabetes; the head of the metatarsal joint of the fifth toe of the right foot has corns, and there are often shoulder injuries; the corns between the second and third toes of the right foot indicate visual impairment of the right eye; Pale edema on the fourth toe side may have hypertension and arteriosclerosis; Second, plantar edema on the three toe side is often accompanied by fundus disease.

A small white shit appears at the base of the toes of the feet as a symbol of high blood pressure; edema at the joints of the plantar toes often indicates pelvic inflammatory disease or pleurisy; edema of the toes is a manifestation of cardio-renal disease; bulges appear in the soles of the feet with multiple hypertensionSystemic stones, depression may be cirrhosis or liver cancer; purple spots of internal complications are more common in gynecological diseases.

Under normal circumstances, touching the foot does not cause an abnormal response.

If you feel acid, numbness, or soreness when you touch the foot, you may also have a certain disease of the limb.

For example, pain is related to neurological diseases; numbness is often caused by skin disorders or blood diseases; acidity is more common in trauma; woody feeling may be inflammation; cold feeling is wind chill; jumping feeling is rupture and rupture; swelling is mostly edema, etc.

Experts say baked sweet potatoes can be eaten as snacks

Experts say baked sweet potatoes can be eaten as snacks

At present, there are many small vendors selling roasted sweet potatoes on the streets of Beijing. Many people will buy a few pieces, and eating a steaming sweet potato on a day when the chill is gradually coming, can be considered a pleasant thing.

  But many people also pointed out that roasted sweet potatoes bought at outside stalls are harmful to health and cannot be eaten.

Is that so?

  Today, Fan Zhihong, associate professor of the Department of Nutrition and Food Safety of China Agricultural University, commented in detail on the reasons why everyone opposed to selling sweet potatoes by small vendors, and talked about the way in it.

  The charcoal fire in the barbecue method can be heated and indirectly roasted. The reason may be opposed: the sweet potatoes sold by small merchants outside are burned with coal, which is harmful to health.

  Expert opinion: Generally speaking, direct open-roast baking is prone to produce harmful substances, mainly acrylamides produced by starches heated at temperatures above 140 ° C, substituted amines produced by protein coke, and produced at slightly high temperatures.Benzo pyrenes.

However, because sweet potatoes are hardly unfortunate and have little protein, they are not dangerous at normal baking temperatures.

  In theory, setting the temperature and time to bake sweet potatoes in an electric or infrared oven is the safest.

But these costs are relatively high and are not suitable for roasting on the road.

And the civilians often use charcoal to indirectly dormant, so small vendors outside are acceptable as long as the sweet potatoes do not directly contact the open flame.

  Most of the sweet potato roasting tools on the street are large round iron buckets, and some even transform chemical buckets into sweet potato barbecue stoves. If the sweet potatoes roasted in this way are eaten, they are definitely not good for the body.

  Expert opinion: Whether roasted sweet potatoes in round iron buckets is harmful depends on what substances they previously contained, which cannot be generalized.

For example, this barrel used to contain alcohol or cooking oil.

  If it was used to hold gasoline, although gasoline itself is not edible, it will completely evaporate after being heated a few times.

After the volatilization is clean, it will no longer bring harmful substances.

Unless it is filled with non-volatile toxic substances, and it is not long after being used up, there is obvious harm.

  Of course, everyone hopes that sweet potato processors can use an infrared or electric oven to bake in a clean room.

In fact, there are indeed such workshops now, making clean and safe baked sweet potatoes for people, this will be its development direction.

However, we don’t need to treat the sweet potatoes baked in round iron buckets as poison, and use this bucket to make a fuss.

  The sweetness of the sweet potatoes that have not been moldy stored for a long time in the baking ingredients naturally rises. Reason: Some vendors will use the stored sweet potatoes for a long time. Although sweet, they may damage the nutritional value.

  Expert opinion: Such roasted sweet potatoes are harmless.

Many potatoes, fruits, vegetables, etc. have this basic characteristic. After cold storage in winter, the sugar content in the raw materials will rise, which is an instinctual biochemical change in plants to improve freeze resistance.

  Therefore, you can rest assured that you have eaten sweet potatoes for half a year. Drying the surface will not hinder the nutritional value, and it will not mold.

It is reminded to note that raw sweet potatoes will produce toxins after they become moldy and black, so do not eat them, or sweet potatoes that are softened and frosty after frostbite, do not eat.

  Do n’t worry if the skin is roasted during the baking process. Just remove it and eat it. Reason: Sometimes, the skin of roasted sweet potatoes often has roasted or even blackened parts, which must contain harmful substances.

  Expert opinion: If it is brown, sticky, basically don’t worry, because this is the result of “caramelization reaction”.

  The sugar in the sweet potato is concentrated at high temperature, and the caramelization reaction occurs when it is heated to more than 140 seconds, and the color gradually becomes darker with the increase of the conversion temperature, and finally becomes black and carbonized, but it is non-toxic.

This process will produce a seductive and sweet smell, which is one of the reasons people love roasted sweet potatoes.

If the skin is not brown at all and the aroma is insufficient, I am afraid that not many people will be tempted.

  Of course, at the same time as the caramelization reaction occurs, the small amount of protein contained in the sweet potatoes will also be burnt together, a Maillard reaction will occur, and acrylamide will be produced.

But don’t worry too much, because the content of sweet potato protein is very low, you can remove the scattered black parts when eating.

  Experts remind children to eat sweet potatoes as a “snack”. It is a starchy food, it is rich in vitamin C, and there are many carotene in the heart.

Surprisingly, the starch contained in sweet potatoes will protect the vitamins in it, and the losses after steaming, boiling, baking, etc. are very small.

  Roasted sweet potato is actually a reasonable processing method. It does not introduce oil or add sugar. It is a natural low-fat, high-fiber food, and it can retain its own properties that help prevent bowel cancer.

  If children use baked sweet potatoes instead of cookies, cakes, cookies, etc., it can be said to be a healthy snack option.

  Especially recommended, in fact, you can also make baked sweet potatoes at home, if you like to eat, you may try.

  1.

Wash the sweet potatoes and heat in a microwave oven for 5-6 minutes on high heat to allow the interior to heat through.Then transfer to the oven, bake at 140 kW for 20 minutes, and then bake for 20 minutes for 100 seconds. After the heat is turned off, cool naturally in the oven to room temperature.

  2.

Wash the sweet potatoes, cut them into thick pieces, put them in the oven lunch box, and heat for 2-5 minutes depending on the number of sweet potatoes pieces; then take a pan, put a small amount of oil on the bottom, spread the pre-heated sweet potato pieces and coverCover, bake on low heat for 10 minutes, turn over and bake for another 8 minutes.

Note that the fire is small, observe often, and avoid bottoming.

10 Health Food Recipes for Honey

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10 Health Food Recipes for Honey

Honey “food therapy” has a history of thousands of years.

Honey is rich in nutrition, containing about 70% of glucose and fructose, and also contains protein, inorganic salts, organic acids, multivitamins, and calcium, magnesium, potassium, phosphorus and other substances.

  Honey radishes are washed with fresh white radishes, cut into dices, boiled in boiling water, controlled to dry, and dried for half a day. Then add 150 grams of honey to the pot, boil over low heat and mix thoroughly.

Suitable for indigestion, nausea, vomiting, and less cough.

  Take the appropriate amount of fresh ravioli juice, wash, slice, and squeeze the juice. Mix and take 1 cup of fresh ravioli juice and 1 tablespoon of honey.

2-3 times a day.

Suitable for fever, thirst, heat stroke and thirst.

Fresh lily honey 50 grams of fresh lily, 1-2 spoons of honey.

Place the lilies in a bowl, stir in the honey, and steam in the drawer.

Take before bedtime, suitable for frequent eating in patients with insomnia.

  100-150 grams of fresh celery with celery honey juice and a moderate amount of honey.

Wash and mash the celery, and stew it with honey and serve warm.

1 time daily.

Suitable for hospitalization of patients with hepatitis.

  Shouwu made from honey Shouwu Danshen juice, 15 grams each of salvia miltiorrhiza and 15 ml of honey.

Make Shouwu, decoction of Salvia miltiorrhiza to remove juice and mix honey, 1 dose per day.

Suitable for those with arteriosclerosis and hypertension.

  Honey 100ml honey, steamed in a bowl.

Take 3 times a day on an empty stomach.

Suitable for patients with gastric and duodenal ulcers.

  Honey milk drink 50 ml of honey, 50 ml of milk, 25 grams of black sesame.

Black sesame is smashed and blended with honey and milk.

Suitable for postpartum blood deficiency.

Intestinal dryness and constipation.

Facial chlorosis, moist skin, etc.

  Honey, walnut meat, honey 1000 ml, walnut meat 1000 g, smashed walnut meat, mix honey, and mix well.

Take 1 spoon each time, 2 times daily with warm water.

Suitable for asthma.

  Moderate amount of honey, 30 grams of ghee, 50 grams of previous rice.

First boil the porridge with rice, butter and honey, and cook a little.

Suitable for yang deficiency and fever, lung cough, cough, thirst, dry skin, aphtha and so on.

  1-2 buttered eggs with honey and 1-2 spoons of honey.

Pound eggs, add honey while hot, eat immediately, even for 2-3 months.

Suitable for children with bronchial asthma.

Let your baby fall in love with meals

Let your baby fall in love with meals

[Materials]650 grams of grass carp, 2 tablespoons of tomato sauce, 2 tablespoons of soy sauce, 3 long red pickles, an amount of dried starch, an amount of peanut oil, 2 tablespoons of water starch, 1 piece of ginger, 2 pieces of garlic, 2 chives, and an appropriate amount of salt2 teaspoons of cooking wine[Practice]① Remove the head of the fish, laparotomy, remove the black film and internal organs in the belly, and cut it into sections after washing.

  ② Cut ginger into ginger foam, chopped shallot white and green onion respectively, garlic into cubes, and chopped red pickled pepper.

  ③Put the fish into the container, add cooking wine, a small portion of ginger foam, light green, and salt for 10 minutes.

  ④ Make each piece of fish evenly covered with dry starch.

  ⑤ Heat the pan, pour in more oil than usual fried eggs, fry the fish pieces over medium and low heat, and slowly fry them into golden brown on both sides and remove.

  ⑥ Lift the wok and add 1 tablespoon of peanut oil. After the oil is hot, add medium to low heat, add pickles, ginger, and garlic fry.

  Add tomatoes and stir-fry with ketchup to color.

  加 Add about 40ml of water, water starch, and soy sauce to the bowl and pour into the pot.

  ⑨ Continue to simmer over medium-low heat until the juice is bright and transparent.

  Add the fried fish pieces and turn gently, or push the pan until the fish pieces are evenly juiced, add the green onions and turn it twice to serve.

Experts on fire in spring to solve hot physique

Experts on fire in spring to solve hot physique

Right now it’s spring, and it’s windy and dry.

When I usually have a bad rest or work pressure, I always feel that my mouth is dry, my nose is easy to bleed, my throat is dumb, my mouth is sore, and I still have a few small acne.It is a manifestation of getting angry.

  When the fire and gas appears, it means that the physiological function of the body loses balance. The fire and gas quickly consume water in the body, leading to dry mouth and dry mouth, and poor neuroregulation ability. People will also be emotionally unstable, feel nervous and easily tired.

  Experts remind: the human body is hot in spring, if you do not pay attention to light diet and regular life, it is easy to “ignite the fire”.

  The following symptoms of getting angry experts teach you how to cope with it: ☆ Sore throat, sore throat, dryness, and pain relief. This is one of the most common “getting angry” symptoms in spring.

Treatment can try the following methods: Spring Qingyan Decoction: chrysanthemum, honeysuckle 10 grams each, raw licorice, fat sea 6 grams each.

Place the medicine in a thermos bottle, brew with boiling water, and drink frequently instead of tea, 1 dose per day.

It has the effect of evacuating wind-heat and pharyngeal voiceless sound.

It is mainly used in the treatment of common acute pharyngitis and tonsillitis caused by spring, sore throat and dry cough.

  ☆ Constipation In spring, especially in the elderly, dry stools often occur.

  To treat constipation caused by Chunzao, it is easy to “run” but not “diarrhea”, you can try the following Runchang diet therapy prescription.

  Sesame and Walnut Soup: Black sesame and walnut kernels (ground) are mixed in an appropriate amount, mixed with honey after cooking, warmed with water, and taken daily.

  Honey Cassia Drink: Stir-fried cassia seeds 15 grams, add an appropriate amount of water, boil it in a casserole and boil it over low heat for 30 minutes. Filter the liquid medicine and add a small amount of honey. Replace it with an empty stomach tea daily.

  Nosebleeds Capillary blood is rich and brittle in the nasal cavity. The dry climate in spring will first endanger the nasopharynx, dry the nasal mucosa, rupture the capillaries, and cause nosebleeds.

In terms of treatment, cold forehead and nasal bridge can be used to temporarily stop bleeding when bleeding. After recovery, 30 grams of white grass root or 15 grams of sacral water can be taken and replaced with tea.

It has the effects of clearing heat, cooling blood, and stopping bleeding.

  ☆ Aphthous ulcers often appear in the mouth inexplicably in the spring. The symptoms reach climax after 3-4 days. In addition to the obvious pain, they are accompanied by systemic symptoms such as low fever and local lymphadenopathy.

After 4-5 days, the redness gradually subsided and the pain was reduced; after 8-14 days, the ulcers could heal by themselves without leaving any traces.

  Seven wonderful recipes for treating oral ulcers: 1.

Apply a small amount of sugar to the ulcer surface 2-3 times a day.

  2.

Use a cotton swab to dip a small amount of ice boron powder and apply it to the affected area. Although it feels a bit bitter, but after persisting for 2-3 days, the wound can be cured.

  3.

The garlic epidermis was torn off, and a transparent film wrapped with garlic cloves was applied to the mouth ulcer.

  4.

Take Huasu tablets, 1-2 tablets each time, 3-4 times a day.

  5,

After cleaning the mouth, apply honey to the surface of the ulcer with a sterile cotton swab, and do not eat or drink for the time being.

After about 15 minutes, you can swallow the honey and continue to apply it. You can apply it several times a day.

  6.

External application of Yunnan Baiyao for oral ulcer wounds, twice a day, usually healed in 2-3 days.

  7.

Eat more tomatoes.

  In fact, it is more important to adjust from the diet and work schedule.

Especially when changing seasons, eat more tomatoes, because it contains a large amount of B, C vitamins, carotene, and calcium, iron, zinc, iodine and other trace elements, eat 2-3 daily, which can effectively prevent the occurrence of oral ulcers.

In addition, drink plenty of water, eat more fruits and vegetables, eat less spicy food, and work properly.

According to severe symptoms, you should go to the hospital for treatment in time and use the combination of Chinese and Western medicine to reduce the frequency of ulcer recurrence.

  ☆ Rotten mouth corner Spring is the season of frequent chapped lips and “rotten mouth corner” (angular inflammation).
In the early stages of this symptom, first of all, the mouth corners appeared flushing, scaling, and rot, and then the corners of the mouth cracked, bleeding, pain, affected the opening of the mouth, and even caused trouble in talking and eating.
  Once dry lips or rotten mouth corners occur, riboflavin treatment should be taken.

Eat more riboflavin foods, some sports foods.

Riboflavin is the most abundant in animal livers, followed by eggs, beef, spinach, amaranth, canola, fennel, peanuts, soybeans, fungus and other foods that also contain considerable amounts of riboflavin.

  Also, eat less hot pot.

Because the chemical properties of riboflavin and other metabolized vitamins are very unstable, they are easily damaged by various factors, such as heating, ultraviolet rays, and alkali.

Hot pot is a long-term cooking food, and most of the riboflavin is destroyed.

  To prevent rotten mouth corners, pay attention to the following points: Pay attention to adjusting your diet, eat as much fresh green leafy vegetables, radishes, carrots and various fruits as possible, and eat soy products, milk, eggs, lean meat, animal liver and other rich B vitamins.Foods to avoid vitamin B deficiency.

Lips can be moisturized by applying lipstick when the corners of the lips are dry to prevent peeling.

  When chapped hemorrhage has appeared in the corner of the mouth, it should be washed with warm water first, the tips should be dried, and some antibiotic ointments such as gold toxins should be applied.

When the wound begins to scab, do not tear it off forcibly, let it fall off naturally.

If infected, go to the hospital for treatment in time.

  Simple and effective “fire extinguishing” small tricks: The first trick is to replenish water at any time. Drinking warm water can solve many problems, including cooling the dry heat in the body, washing bacteria in the mouth, inhibiting bacterial growth, and even staying in air-conditioned rooms.Drink about 1300cc a day.

Drink more water when sweating. It is suitable to drink lemonade when you are on fire. Eat more sour fruits such as citrus. If you do not like the tastelessness, you can also drink soothing tea, such as mint, bitter tea, and chrysanthemum., Honeysuckle and other herbal teas.

  The second measure is to improve the quality of sleep. People who sleep poorly will easily get angry, and upside down day and night is even more taboo.

For people who work mentally in surgery, the blood circulation will be concentrated on the head, resulting in tiredness but instable sleep. At this time, you can use the foot bath to bring the fire down.

The method is as follows: first soak in warm water (female water should accumulate to two thirds of the calf near Sanyinjiao, and men can replace the feet), then slowly heat the water, soak the feet until the feet are hot, and sweat slightly to rest.

A foot bath is very helpful to improve the skin surface loop. After soaking for a week, you will find that it is more and more prone to sweating, and the skin will not dry even in the air-conditioned room.

  The third measure is to eat light and high-metabolized foods to provide anger. When you are on fire, you should not eat more low-moisture foods, such as fried nuts, biscuits, peanuts and other nuts. Switch to low-calorie diets such as vegetables and clear soup.

  Spring “getting angry” in the spring, life must be regular, pay attention to work and rest, rest on time.

Eat more vegetables and fruits quickly and less spicy foods.

Drink plenty of water or drink hot beverages. It is also important to stay positive and optimistic.

Fabry disease shows pain in the limbs

Fabry disease shows pain in the limbs

Most patients with typical Fabry disease develop from childhood to puberty, with skin or nervous system symptoms at the beginning: fingers, scalp and other limbs with recurring burning or knife-like pain, and extremity paresthesia are the first nervous systemsSymptoms, exercise, fatigue, infection, fever, etc. are often causative factors. Once a few hours to several calendar days have passed, it may be accompanied by swelling of the hands and feet, fever, and rapid increase in erythrocyte sedimentation. A small number of children are accompanied by abdominal pain, diarrhea.All returned to normal; typical skin lesions were most often found between the umbilicus and knee.

  Fabry disease is a deficiency of alpha-galactosidase A caused by X-linked recessive inheritance. Deficiency of this enzyme causes trihexosylceramide to fail to metabolize and accumulate in the body.

Involved hemizygous men show clinical signs with an incidence of about 1/40000; a small number of atypical hemizygous men may be asymptomatic or show only mild heart or kidney involvement; women with heterozygotes are clinicallyIt is normal, or there are only mild symptoms.

Alpha-galactosidase A encodes a locus xq22.

1. Molecular biology research shows that there are many types of gene mutations that cause this disease, including point mutations, partial deletions, insertions, and mRNA splice junction defects.

Defects in α-galactosidase A cause glycosphingolipids such as trihexosylceramide and digalactosylceramide to accumulate in the blood circulation, vascular wall epithelial cells and smooth muscle cells in the cytoplasm and lysosomes., Causing extensive distortion, involving the skin, muscles, brain, kidneys and other system organs.

Because one of the sources of this glycosphingolipid is type B erythrocytes, male patients with type B or AB are particularly ill.

  Most of the typical patients are from childhood to adolescence, with skin or nervous system symptoms as the beginning: recurring burning or knife-like pain in the extremities such as toe bones and paresthesia are the first neurological symptoms.Exercise, fatigue, infection, fever, etc. are often the predisposing factors. Occasionally, a few days to several weeks can be accompanied by swelling of the hands and feet, fever and rapid increase in erythrocyte sedimentation. A small number of children are accompanied by abdominal pain, diarrhea.Normal; typical skin lesions are most common between the umbilicus and the knee, and can also be seen in the oral mucosa, legs, buttocks, etc., which are symmetrically distributed, dark red or blue-black spots or microconvex papules from the needle tip to a few mm in diameterIt does not fade, it is called angiokeratoma. The size and intensity of the rash increase with age, and most of them are accompanied by hypohidrosis.

  Most of the children have ocular symptoms. The corneal opacity can be found early with slit lamp inspection. At first, diffuse cloud-like changes appear in the deep layers of their epithelial cells. Then, straight or flexed thin lines spread from around the cornea to the center. This is the disease.Characteristic performance; the combined membrane and omental vessels can be zigzag.

Skin and eye symptoms may appear at the same time as neurological symptoms, or they may precede neurological symptoms.

Renal vascular disease can occur in childhood proteinuria, red blood cells and casts in urine, etc .; metastasis progresses, patients in 20?
At the age of 40, he showed signs of renal decline such as isotonic urine and azotemia.

Cardio-cerebral vascular disease: hypertension, left heart hypertrophy, myocardial infarction and infarction, cardiovascular failure and other manifestations of heart failure and cerebral infarction gradually occur in middle age.

In the advanced stage of the disease, patients often have pulmonary insufficiency, aphasia, epilepsy, and hemiplegia; most of them are in the 40?
He died of uremia, heart failure or sudden brain death at the age of 45.

  A few mild patients are clinically asymptomatic, or only see proteinuria, cardiovascular symptoms, or paresthesia only. Such patients still have some residual enzyme activity.

  The diagnosis of this disease requires: ① determination of α-galactosidase A activity in plasma, leukocytes, tears or cultured fibroblasts, which is often undetectable in typical patients; ② trihexosyl in plasma or urine (sediment)The ceramide content can be measured, and the lipid particles in urine can be detected by plasma light microscopy.

  For women suspected of being heterozygous, RFLP can also be used for analysis and detection; enzymatic or molecular biological detection of villi or amniotic fluid cells can be used for prenatal diagnosis.

  Patients should avoid exposure to the sun and high temperatures, and ensure adequate drinking water to reduce pain; phenytoin or carbamazepine can relieve pain and relieve acromegaly; thiefidine and aspirin can inhibit platelet aggregation and can be used to prevent vascular embolism.

Electrostatic pollution hazards of home appliances

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Electrostatic pollution hazards of home appliances

Static electricity is a common phenomenon in life. Electrostatic pollution generated by household appliances causes vacuuming, which affects the use effect, and sometimes may even harm human health.

銆€銆€During the dry season, the semiconductor radio will make a loud noise, because the built-in double-filled variable capacitors and plastic film accumulate static electricity in the rotating friction.

The cutting-edge method is to use a cotton ball to rub the ethanol, drop it into the four fixing screw holes of the variable capacitor, and then rotate the tuning knob once and again.

銆€銆€If the recorder is playing, every second will produce a click, which is caused by the plastic pointing wheel and belt friction of the recorder. The rescue method is to apply a little oil on the side of the inertia wheel, or in inertia.Apply a little varnish to the metal parts near the wheel to avoid placing the electronic watch.

銆€銆€The plastic fan blades of the electric fan and the air friction generally generate static electricity with positive static electricity.

This kind of static wind will neutralize the negative ions in the air, causing obstacles in people’s physiological activities, such as nausea, arrogance, fatigue and other symptoms. The solution is to spray anti-static paint on the fan blades, or buy an electric fan with metal blades.

銆€銆€Color TV, especially large-screen color TV, because the electron beam emitted by the tube electron gun acts on the screen, converting the screen and the nearby air to a higher voltage static electricity.

The dust in the air initially becomes charged particles.

This charged particle is adsorbed in the pores of a person’s face and forms a black spot.

銆€銆€The prevention method is: First, wash the face with facial cleanser after watching TV; Second, replace the TV with protective glass.

銆€銆€The outer casing of electric hair dryers, refrigerators, washing machines, etc. can also carry static electricity, and the static spark generated may even cause the leaking gas to explode.

In order to ensure safety, the refrigerator and the washing machine casing must be properly grounded, so that the accidents of electric leakage of the electrical casing can be prevented.